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 Got the flu? Take this article to your doctor!

11.07.19.  When an old remedy is better that anyone can remember. If you had the flu jab and still got the flu, as many have done, clip this article and show it to your doctor—he or she may nor be aware of new findings that may work—the concept makes sense to this struck off now retired lobotomy mechanic.
A medication used in World War II as an antidiuretic is one of two drugs that Melbourne researchers believe could reduce the number of people that die from the flu every year. Influenza cases have surged Australia-wide in 2019 and the death toll has climbed to about 300 in a season that has been described as “brutal”. A two-year-old boy in WA is thought to have died from the virus and teenagers thought to be perfectly healthy have died after getting the flu.

Source: ABC

Flu deaths could be prevented with a drug used during WWII, researchers find

The flu vaccination can prevent people from getting sick, but until now little has existed to help sufferers in the middle of severe and potentially fatal cases of the virus.
Researchers at Melbourne’s Hudson Institute of Medical Research have identified two drugs — the anti-diuretic Probenecid and an anti-arthritis medication — that could change that.
“The potential for these drugs is enormous. Obviously, there is a massive worldwide global health burden for influenza infections,” scientist Ashley Mansell said.
“And therefore the applications are huge and have a massive capacity to make a real difference to health outcomes, particularly to the flu, across the world.”
The Hudson Institute has spent the past decade looking at how to reduce over-inflammation in the host rather than how to attack the virus, which is becoming increasingly resistant to drugs.
The flu can kill in several ways, but over-inflammation is the primary culprit.
“Inflammation is our friend, inflammation is good, but sometimes it becomes too much. That causes tissue damage, and that is what can actually cause lethality,” Associate Professor Mansell said.
The drugs could dampen inflammation symptoms such as fever, chills, swelling, joint paint and redness, which the researchers hope could save lives.
Probenecid was developed in the 1940s and used during World War II to prolong the life of penicillin, and is now used to treat gout.
Researcher Michelle Tate said the drug had a “very good safety profile” after being used for decades.
The second drug identified by the institute as a potential weapon against flu deaths is known as AZ11645373 and has been clinically trialled for treating arthritis.
In findings published in the British Journal of Pharmacology today, the scientists said both drugs target a molecule — the ATP receptor P2X7 — that plays a key role in inducing inflammation.
Associate Professor Mansell said the flu had become “very smart” and “mutates at an excessive rate” so anti-viral medication had become less effective in prevention.
The research suggests the way the drugs interact with the immune system to slow inflammation could save the lives of people once they contracted severe cases of influenza.
Dr Tate, who authored the journal report, said the fact these drugs already exist was a huge boost to the research and development phase.
“We could re-purpose them for the flu, much quicker than if we were to design a brand new drug,” she said.
It could be years before the drugs are available on the market to treat influenza and the team needs to confirm how they would be administered to flu patients.
The institute is now trying to collaborate with other health authorities for clinical trials to treat Avian flu and other severe influenza infections.
Associate Professor Mansell said the P2X7 molecule was involved other illnesses and the drugs could be also used to treat other health problems in the future.
“Infectious disease, what we call sterile diseases, things like gout, things like cancer even, it has been implicated in. And therefore, these drugs may have applications further than just actually treating the flu,” he said.

{ 6 comments… add one }
  • luk1955 11/07/2019, 7:29 am

    I bet those drugs cost a lot more than vaccine shots. My BIL and wife both had flu vaccine shots and both now have the flu.

    • Deano 11/07/2019, 11:15 am

      SShhh! Mustn’t talk about that.

  • Muphin 11/07/2019, 7:36 am

    Best anti flu cure is 3000mg of vitamin C during the flu season then 1000mg daily. Flu Vac helps but the rest are placebos that make the manufactures RICH.

  • Eliza 11/07/2019, 8:45 am

    The best anti cold/flu remedy is small clove of garlic daily. Did it all my life till recently as it is also a blood thinner and now I have had to cut it out as I bleed to easily when scratched etc. I never had colds/flu until I gave it up. As to the garlic smell it didn’t worry those that cared!!!!

  • Penguinite 11/07/2019, 8:47 am

    I am or was a vaccination convert until my last visit to the doc, last week, just generally chatting with the Practice Nurse she told me that they (the system) had experienced a huge failure rate with this years model. The failure hasn’t affected us, YET, but there’s still time. Best way to stop the germ mutating is to reduce human interaction when the bug is abroad. If you get sick stay at home!

  • Botswana O'Hooligan 11/07/2019, 9:17 am

    For what it’s worth, I never got a cold or the ‘flu n the doctor told me that people who have cancer generally don’t get a cold or the ‘flu. but now I get the odd cold since the cancer has gone away (I hope) but no flu. Maybe the doctor was right but we are all different and the so called “first people” are out to prove that they are really different, and superior to us as well.

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